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儿童反应性血小板增多症相关临床疾病的探讨

A study on clinical diseases associated with reactive thrombocytosis in children

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【作者】 许海俐徐军

【Author】 Xu Haili;Xu Jun;Department of Clinical Laboratory,Nanjing University of Chinese Medicine/the Second Traditional Chinese Medicine Hosptial of Jiangsu;Department of Clinical Laboratory,Children′s Hospital Affiliated to Medical School of Zhejiang University;

【机构】 南京中医药大学第二附属医院江苏省第二中医院检验科浙江大学医学院附属儿童医院检验科

【摘要】 目的探讨儿童反应性血小板增多症(RT)的相关临床疾病。方法将血小板计数(PLT)>500×109/L的3 065例RT患儿纳入调查,根据PLT将其分为4组:A组(PLT:>500×109/L~700×109/L,n=2 533)、B组(PLT:>700×109/L~900×109/L,n=434)、C组(PLT:>900×109/L~1 000×109/L,n=61)和D组(PLT:>1 000×109/L,n=37)。分析各组患儿的原发疾病。结果患儿RT的总发病率为8.5%(3 065/36 000)。RT的发病随患儿年龄的增加而减少,其中,1岁以内患儿RT的构成比为72.0%(2 206/3 065)。4组患儿以PLT轻度增高为主(82.6%,2 533/3 065),疾病种类包括肺炎,其他感染,组织损伤(烫伤、烧伤及骨折等)及其他疾病,其中,肺炎所占百分比最大,为51.4%(1 574/3 065)。结论 RT患儿以感染性疾病多见,尚无与RT相关联的严重并发症发生。

【Abstract】 Objective To explore the clinical diseases associated with children reactive thrombocytosis(RT).Methods 3 065 children with RT and platelet count(PLT)over 500×109/L were enrolled in the investigation and were divided into four groups according to PLT:group A(PLT:>500×109/L-700×109/L,n=2 533),group B(PLT:>700×109/L-900×109/L,n=434),group C(PLT:>900×109/L-1 000×109/L,n=61) and group D(PLT:>1 000×109/L,n=37).The primary diseases of the children in each group were analyzed.Results The overall incidence of RT was 8.5%(3065/36000)in the investigated children.With the increasing age,the incidence of RT decreased,and the RT incidence of children less than one year of age was 72.0%(2 206/3 065).Slightly elevated PLT(82.6%,2 533/3 065) was major in children of the four groups,and the types of disease were pneumonia,other infections,tissue damage(scalding,burns,bone fractures,etc.)and other diseases.Among them,the percentage of pneumonia was maximum,51.4%(1 574/3 065).Conclusion Infectious diseases are more common in children with RT and yet no serious complications associated with RT is found.

【关键词】 血小板增多症血小板计数疾病儿童
【Key words】 thrombocytosisplatelet countdiseaseschild
  • 【文献出处】 国际检验医学杂志 ,International Journal of Laboratory Medicine , 编辑部邮箱 ,2013年21期
  • 【分类号】R725.5
  • 【被引频次】2
  • 【下载频次】94
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