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儿童反应性血小板增多症相关临床疾病的探讨
A study on clinical diseases associated with reactive thrombocytosis in children
【摘要】 目的探讨儿童反应性血小板增多症(RT)的相关临床疾病。方法将血小板计数(PLT)>500×109/L的3 065例RT患儿纳入调查,根据PLT将其分为4组:A组(PLT:>500×109/L~700×109/L,n=2 533)、B组(PLT:>700×109/L~900×109/L,n=434)、C组(PLT:>900×109/L~1 000×109/L,n=61)和D组(PLT:>1 000×109/L,n=37)。分析各组患儿的原发疾病。结果患儿RT的总发病率为8.5%(3 065/36 000)。RT的发病随患儿年龄的增加而减少,其中,1岁以内患儿RT的构成比为72.0%(2 206/3 065)。4组患儿以PLT轻度增高为主(82.6%,2 533/3 065),疾病种类包括肺炎,其他感染,组织损伤(烫伤、烧伤及骨折等)及其他疾病,其中,肺炎所占百分比最大,为51.4%(1 574/3 065)。结论 RT患儿以感染性疾病多见,尚无与RT相关联的严重并发症发生。
【Abstract】 Objective To explore the clinical diseases associated with children reactive thrombocytosis(RT).Methods 3 065 children with RT and platelet count(PLT)over 500×109/L were enrolled in the investigation and were divided into four groups according to PLT:group A(PLT:>500×109/L-700×109/L,n=2 533),group B(PLT:>700×109/L-900×109/L,n=434),group C(PLT:>900×109/L-1 000×109/L,n=61) and group D(PLT:>1 000×109/L,n=37).The primary diseases of the children in each group were analyzed.Results The overall incidence of RT was 8.5%(3065/36000)in the investigated children.With the increasing age,the incidence of RT decreased,and the RT incidence of children less than one year of age was 72.0%(2 206/3 065).Slightly elevated PLT(82.6%,2 533/3 065) was major in children of the four groups,and the types of disease were pneumonia,other infections,tissue damage(scalding,burns,bone fractures,etc.)and other diseases.Among them,the percentage of pneumonia was maximum,51.4%(1 574/3 065).Conclusion Infectious diseases are more common in children with RT and yet no serious complications associated with RT is found.
- 【文献出处】 国际检验医学杂志 ,International Journal of Laboratory Medicine , 编辑部邮箱 ,2013年21期
- 【分类号】R725.5
- 【被引频次】2
- 【下载频次】94