【摘要】 目的探讨丙型肝炎病毒核心抗原(HCV-cAg)检测对丙型肝炎病毒(HCV)感染诊断的价值。方法随机选取于该院检验科做HCV抗体(HCV-Ab)检测的215例血液标本,采用试剂盒进行检测,首先检测HCV-Ab,根据HCV-Ab检测结果分为HCV-Ab阳性组和HCV-Ab阴性组。同时检测两组的游离HCV-cAg、总HCV-cAg、HCV-RNA。结果 HCV-Ab阳性组(97例)中,游离HCV-cAg阳性占25.8%(25/97),总HCV-cAg阳性占71.1%(69/97),HCV-RNA阳性占68.4%(66/97);HCV-Ab阴性标本组(118例)中,游离HCV-cAg阳性占1.7%(2/118),总HCV-cAg阳性占2.5%(3/118),HCV-RNA阳性占1.7%(2/118)。结论 HCV-cAg的检测有利于HCV感染的早期诊断。更多还原

【Abstract】 Objective To investigate the value of the hepatitis C virus core antigen ( HCV-cAg ) detection for the diagnosis of hepatitis C virus (HCV) infection.Methods 215cases of hepatitis C antibody (HCV-Ab ) test specimen in the hospital were collected for the study.Test kits were used to detect HCV-Ab firstly , then the specimen were divided into HCV-Ab positive group and negative group , for which free HCV-cAg , total HCV-cAg , HCV-RNA were detected at the same time.Results There were 97 cases of HCV-Ab positive , free HCV-cAg positive accounted for 25.8% (25/97), the total HCV-cAg positive 71.1% (69/97 ), HCV-RNA positive 68.4% (66/97); there were 118cases of HCV-Ab negative , free HCV-cAg positive accounted for 1.7% (2/118), the total HCV-cAg positive 2.5% (3/118), HCV-RNA positive 1.7% (2/118) .Conclusion HCV-cAg test is useful for early diagnosis of HCV infection.更多还原