【摘要】 目的探讨2型糖尿病合并骨质疏松症的相关因素。方法 50例2型糖尿病合并骨质疏松症患者为骨质疏松组,年龄32～78岁;52例骨密度正常的2型糖尿病患者为非骨质疏松组,年龄34～75岁。采用美国GE公司产的双能X线骨密度仪测定入组患者股骨颈、腰椎2-4(L2-4)骨密度,并分析其与性别、年龄、糖尿病病程、糖化血红蛋白水平、体重指数(BMI)、尿微量白蛋白、糖尿病大血管病变、低密度脂蛋白水平等的相关性。结果骨质疏松症的发生与糖尿病患者性别、年龄、病程、糖化血红蛋白、尿微量白蛋白呈正相关,P值分别为0.030、0.006、0.015、0.024、0.002;与BMI呈负相关(P=0.032);与糖尿病大血管病变、低密度脂蛋白无相关性。结论 2型糖尿病患者尤其是女性的年龄、糖尿病病程延长、糖化血红蛋白升高及尿微量白蛋白增高与骨质疏松症相关。更多还原

【Abstract】 Objective To explore the influence of type 2 diabetic patients with osteoporosis-related factors.Methods Selected 50 patients with type 2 diabetic aged 32-78 years old asscoicated with osteoporosis, 52 type 2 diabetic patients aged 34-75 years old with normal bone mineral density as the control. The bone mineral density of all patients including lumbar spine, femoral neck were detected using dual-energy X-ray absorptiometry produced by the U.S. company GE. The correlation analysis of gender, age, duration of diabetes, glycosylated hemoglobin, body weight index, microalbuminuria, diabetic vascular disease, low-density lipoprotein and BMD was performed. Results The correlation of osteoporosis in type 2 diabetes with gender,age, duration of diabetes, glycosylated hemoglobin, body weight index, microalbuminuria was found out and had a statistical significance but no significant correlation with diabetic vascular disease, low-density lipoprotein. Conclusion Extend with age, duration of diabetes, elevated glycosylated hemoglobin and urine albumin appears, type 2 diabetes patients, especially female patients were more susceptible to osteoporosis. To control the serum blood glucose and complications progress in diabetes is helpful to prevent the occurrence of osteoporosis to a certain extent.更多还原