【摘要】 目的探讨某院综合重症监护室(ICU)住院患者发生多重耐药菌(MDRO)感染情况及干预效果。方法对该综合ICU进行目标性监测并制定相应干预措施,比较干预前后MDRO医院感染发生情况。结果共调查1 184例患者,发生MDRO医院感染77例次,社区感染109例次;检出MDRO 186株,检出率为15.71%,菌种以鲍曼不动杆菌(43.55%)、耐甲氧西林金黄色葡萄球菌(29.57%)、铜绿假单胞菌(23.66%)为主。MDRO医院感染部位以呼吸道感染率(79.22%,61/77)最高。经干预后,综合ICU医院感染MDRO的发生率由6.92%(38/549)降至4.25%(27/635),差异有统计学意义(χ2=4.04,P<0.05)。结论 MDRO是综合ICU患者医院感染的重要病原菌,采取有效干预措施可减少其医院感染的发生。更多还原

【Abstract】 Objective To evaluate the occurrence and intervention effectiveness on multidrug-resistant organism(MDRO) infection in general intensive care unit(ICU) patients.Methods Targeted monitor and proper measures on general ICU were performed,the occurrence of MDRO infection before and after infection was compared.Results A total of 1 184 patients were investigated,there were 77 cases of healthcare-associated infection(HAI) and 109 community-associated infection,186(15.71%) isolates of MDROs were isolated,the main bacteria were Acinetobacter baumannii(43.55%),methicillin-resistant Staphylococcus aureus(29.57%),and Pseudomonas aeruginosa(23.66%).The major infection site was respiratory tract(79.22%,61/77).After intervention,MDRO infection in this ICU decreased from 6.92%(38/549) to 4.25%(27/635),the difference was significant(χ2=4.04,P<0.05).Conclusion MDROs are important pathogens in HAI in general ICU patients,effective measures can reduce the occurrence of MDRO infection.更多还原