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FDP注射泵注射对心肌损害患儿肌酸激酶同工酶与疼痛的影响

Effect of FDP injection pump on the creatine kinase isoenzyme and pain of the children with myocardial damage

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【作者】 罗淑媛周莉周静覃英覃芳华曾慧琼潘旻

【Author】 LUO Shu-yuan;ZHOU Li;ZHOU Jing;The Pediatrics Department of the People’s Hospital of Guilin;

【机构】 桂林市人民医院儿科

【摘要】 目的:通过1,6-二磷酸果糖(FDP)3种注射泵法比较,找出改善患儿心肌损害同时减轻注射疼痛的方法。方法:观察A、B、C组各60例心肌损害患儿(≤3岁),注射泵注射FDP,用量150mg·kg-1·d-1,分别于15min、20min、25min注射完各20例,注射前后用生理盐水6ml冲管,A组为FDP原液;B组为FDP与生理盐水1∶1比例稀释;C组为FDP与注射用水按1∶1比例稀释。研究3组FDP液不同时间注射对肌酸激酶同工酶(CK-MB)值及注射相关疼痛的影响。结果:B组注射20min时CK-MB下降最明显,差值为(74.5±69.62)U/L;而FLACC评分分值最低(1.75±1.02)分。结论:FDP生理盐水稀释组输注20min时CK-MB下降明显,且FLACC评分低。

【Abstract】 Objective:Through the comparision of 3kinds of injection pumps of the 1,6-fructose diphosphate(FDP),to find out the way to improve the myocardial damage and reduce the pain of injection in children.Methods:60children(≤3years)with myocardial damage in each group were injected FDP by injection pump.Children in Group A,Group B and Group C were respectively injected with the dosage of FDP150mg·kg-1·d-1,before and after injection the pipes were flushed with 6ml physiological saline.The respective 20cases in each group were injected at 15mins,20mins and 25mins respectively.Group A were injected with FDP stock solution;Group B with 1∶1dilution of FDP and physiological saline,and Group C with 1∶1dilution of FDP and water.The effect of different FDP injection at different time on the value of CK-MB and related pain of the patients in three groups were studied.Results:The value of CK-MB decreased the most obviously(74.5±69.62)U/L in Group B when injected at 20mins,and the FLACC score(1.75±1.02)was the lowest.Conclusion:For the group of FDP diluted with physiological saline infused at the time of 20mins,the value of CKMB decreased obviously and FLACC score lower.

【基金】 广西壮族自治区卫生厅自筹项目(Z2012384)
  • 【文献出处】 华夏医学 ,Acta Medicinae Sinica , 编辑部邮箱 ,2013年05期
  • 【分类号】R725.4
  • 【下载频次】14
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