AIM:To study the therapeutic effect and safety of local injection of Bleomycin A5 for the treatment of eyelid xanthelasma. METHODS:Bleomycin A5(0.8g/L) was injected directly into the mass of xanthelasma, 1/10d; 135 patients 256 eyes were enrolled in the study and the therapeutic effect was observed. RESULTS:All the patients were followed up for 3-24 months, 8 eyes were cured by two injections, 32 eyes were cured by three injections, 198 eyes were cured by four injections, 18 eyes were cured by four more inj...