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检测有机磷的聚合物负载荧光探针的研究进展

Research Progress of Polymer-supported Fluorescent Probes for Detection of Organophosphates

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【作者】 张红兴危仁波陈传治庹新林王晓工

【Author】 ZHANG Hong-xing1,WEI Ren-bo1,CHEN Chuan-zhi2,TUO Xin-lin1,WANG Xiao-gong1*(1.Polymer Research Institute,Department of Chemical Engineering,Laboratory of Advanced Materials, Tsinghua University,Beijing 100084,China; 2.Department of Chemical Defense,Institute of Chemical Defense,Beijing 102205,China)

【机构】 清华大学化工系高分子研究所教育部先进材料重点实验室防化学院三系

【摘要】 有机磷农药在农业生产中被广泛使用,由于其对生物体内乙酰胆碱酶的活性具有抑制作用,造成组织中神经递质乙酰胆碱的积累,从而阻断神经信号的传递过程,严重时将导致机体死亡。因此,对环境中的有机磷农药进行快速准确的检测具有十分重要的意义。荧光化学传感器对有机磷酸酯类化合物的检测具有灵敏度高、响应速度快和检出限低的优点。本文综述了国内外聚合物负载的有机磷荧光探针最新研究进展,对其在有机磷检测中的优势进行了讨论和小结,并对该类研究的趋势和未来前景进行了展望。

【Abstract】 Organophosphorus pesticides are widely used in agriculture production at present.Organophosphates can irreversibly combines acetylcholinesterase to inhibit the catalytic active sites of acetylcholinesterase in nerve-impulse transmission,which leads to nerve disease through accumulation of acetylcholine,even causes death.The serious threat of organophosphates to biological systems has stimulated intensive studies to develop sensitive and selective methods for detection of these compounds.Fluorescent chemosensor has attracted considerable attention due to its high sensitivity,rapid response and low detection limit to organophosphates.In this article,recent research progresses on the design and fabrication of polymer-supported fluorescent probes are reviewed,and their advantages in the detection of organophosphates are discussed and summarized.New trends and future perspectives of this research area are also proposed.

【基金】 中国人民解放军总装备部陆装科订部2008CD 012
  • 【文献出处】 高分子通报 ,Polymer Bulletin , 编辑部邮箱 ,2013年07期
  • 【分类号】O631.3;O657.3
  • 【下载频次】392
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