【摘要】 目的回顾18例胰腺实性假乳头状瘤(SPPT)的临床病理特点及治疗,以求建立最佳诊断方法及手术治疗方案。方法回顾近12年18例SPPT患者的术前、手术、术后资料,包括年龄、性别、症状体征、实验室检查、手术、病理及复发和预后情况。结果 18例患者中女性16例,男性2例,平均年龄30.9岁。所有患者均没有特异的实验室检查阳性结果,肿瘤标记物均基本正常。17例患者均获得手术切除肿瘤。平均术后住院日10.7 d,(随访时间3~113个月)。切除患者均无复发。术前影像学中肿瘤的大小、包膜、囊实性比例同胰腺实性假乳头状瘤的良恶性无明显关系。结论该研究证实SPPT是多发于青年女性的少见肿瘤。手术切除是治愈该疾病的治疗方式。更多还原

【Abstract】 Objectives To examine the clinicopathological characteristics and treatment of 18 patients with Solid pseudopapillary of the pancreas(SPPT),to establish the optimal diagnostic method and surgical management.Methods We reviewed the pre-,intra-and postoperative data on 18 patients with SPPT who underwent resection during a 12-year period.Data including demographic information,presenting symptoms and signs,laboratory studies,extent of operation,histology,recurrence and prognosis were evaluated.Results 16 of all 18 patients were women.The other 2 cases are men.The mean age is 30.9.All 18 cases have not been associated with specific clinical laboratory test findings including serum tumor markers.CT and ultrasound can find the tumor in all 18 patients.17 cases of SPPT were resected.Mean postoperative hospital stay was 10.7 days.Patients with tumor resected are alive and well without recurrence,with a follow-up range 3 ~ 113 months.The diameter of tumor,the percents of solid substance and the capsule are not associated with malignant solid-pseudopapilIary tumor of pancreas.Conclusions This study demonstrated that SPPT are uncommon,usually occur in a young woman.Patients required major pancreatic resection to cure the disease.Surgery is curative regardless of the size or location of the tumor.更多还原