【摘要】 目的总结分析羊水栓塞(amnionic fluid embolism,AFE)致孕产妇死亡病例特点,找出诱发因素,探讨预防措施。方法对北京市1996年至2010年67例AFE致孕产妇死亡病例进行回顾性分析。结果 1996年至2010年AFE孕产妇死亡占孕产妇死亡总数的19.20%,居死因顺位第1位,羊水栓塞死亡专率为3.99/10万,2006年至2010年段与前两个年段相比AFE死亡率明显下降,差异有统计学意义(P<0.05);缩宫素使用、胎膜早破、经产妇、高龄产妇和剖宫产是AFE前5位诱因。结论北京市AFE死亡率整体呈下降趋势,但仍居孕产妇死因顺位第1位。严格使用缩宫素、减少分娩干预、规范产检是降低AFE孕产妇死亡率的重要措施。更多还原

【Abstract】 Objective To identify the risk factors and preventions of maternal death caused by amniotic fluid embolism (AFE).Methods Retrospective analysis was used to analyze clinical data of maternal deaths from 1996 to 2010 in Beijing.Results In the past 15 years, maternal death caused by AFE was accounting for 19.20% of the total maternal death in Beijing. AFE was the first cause of maternal death. Average mortality of maternal death caused by AFE was 3.99 per 100 000. Compared with the first two stages, the average mortality of maternal death caused by AFE was significantly decreased from 2006 to 2010. The top five reasons of AFE were using oxytocin, premature rupture of membrane, pluripara, elderly parturient and cesarean-section.Conclusions During the past 15 years, the maternal death caused by AFE is decreased overall, however, it is still the first cause of maternal death. Stricting oxytocin usage, reducing intervention during delivery and standardizing prenatal examinations are important measurements to decrease maternal mortality caused by AFE.更多还原