【摘要】 目的:观察肝癌介入栓塞治疗术前和术后口服盐酸羟考酮控释片(奥施康定)疼痛治疗效果及其不良反应,探讨合理可行的介入栓塞治疗镇痛方法。方法:90例肝癌介入栓塞术患者,术前1h口服奥施康定10mg,术后口服奥施康定10mg q12h×3d,观察统计镇痛效果及相关副作用。结果:术后12h疼痛发生率为32.2%,24h为8.9%,术后48h后疼痛发生率稳定在3.3%,其中重度疼痛发生率为0。结论:口服奥施康定可有效控制肝癌介入栓塞治疗术中和术后的疼痛,不良反应轻,服用安全。更多还原

【Abstract】 Objective:To observe the analgesic effect and adverse effect of oral administration Oxycontin(Oxycodone Hydrochloride Controlled-release Tablets) before and after Transcatheter arterial chemoembolization(TACE) treatment of hepatic carcinoma,discuss the reasonable and feasible pain control method for TACE.Methods:90 patients were given 10mg Oxycontin 1h before the interventional therapy,and after operation 10mg for every 12h for 3 days.The efficacy and side effects were observed and recorded.Results:12 and 24 hours after interventional therapy,the incidences of pain were respectively 32.2% and 8.9%.48h after TACE,the incidences of pain were remained around 3.3%.Among all patients,incidence of severe pain is zero.Conclusion:Oral treatment of Oxycontin can be effective in controlling pain of interventional therapy in hepatic carcinoma,less adverse reactions and take safety.更多还原