An epidemic of rash and fever illnesses suspected of hand,foot and mouth disease(HFMD) occurred in Gansu Province of China in 2008,laboratory tests were performed in order to identify the pathogen that caused this epidemic.Eight clinical specimens collected from the 4 patients(each patient has throat swab and herpes fluid specimens) with rash and febrile illness,were inoculated onto RD and HEp-2 cells for virus isolation,and the viral nucleic acid was then extracted with the positive virus isolates,the dual...
手足口病(Hand,foot and mouth disease,HFMD)是由多种人肠道病毒(Human enterovirus,HEV)引起的常见传染病,其主要临床特征为发热和手、足、口腔和臀部等部位出现皮疹,患者主要为学龄前儿童,尤以3岁及以下年龄组发病率最高[1]。绝大多数HFMD患者预后良好,但少数严重的患者会出