【摘要】 目的探讨冷冻诊断在甲状腺疾病诊断中的临床意义及误诊原因。方法由高年资病理医师对948例甲状腺病变组织的冷冻切片进行复习,对比石蜡切片诊断结果进行分析。结果 948例甲状腺疾病中,恶性肿瘤312例,良性病变636例。冷冻诊断与石蜡切片诊断完全符合和基本符合(确诊)920例,确诊率97.05%;与石蜡切片诊断病变性质不同(误诊)18例,误诊率1.90%,均为假阴性漏诊;延迟诊断10例,占1.05%。结论冷冻诊断对甲状腺疾病术中定性诊断有重要意义。取材准确,提高制片质量和诊断水平,有助于提高冷冻诊断的准确率。更多还原

【Abstract】 Objective To assess the value of frozen section in the diagnosis of thyroid diseases and the reasons of diagnostic errors. Methods A review of 948 frozen sections of thyroid diseases was done by a senior pathologist.The results were compared with that of the paraffin. Results Of the 948 cases reviewed,malignant tumors were confirmed in 312,and benign in 636.The diagnosis made by frozen section was consistent with the paraffin method in 920 cases(97.05%),and that inconsistent(diagnostic errors) with the paraffin found in 18(1.90%),being false-negative missed diagnosis.The diagnosis was delayed in 10(1.05%). Conclusion Frozen section has a great significance in qualitative diagnosis of thyroid diseases at surgery.Accurate material-taking,improvement of slice quality and level of diagnosis are conducive to the accuracy of diagnosis by employing this technique.更多还原