【摘要】 目的探讨颈动脉斑块与缺血性脑卒中的相关性,并分析彩色多普勒超声在缺血性脑卒中的应用价值。方法彩超检查经临床确诊的244例缺血性脑卒中患者(卒中组)的颈动脉,测量并记录颈总动脉内中膜厚度(IMT)与斑块大小与数目,并与81例非心脑血管疾病者进行比较,按年龄段分层分析缺血性脑卒中患者颈动脉斑块及颈动脉狭窄发生的差异性。结果卒中组244例患者中有不同程度IMT增厚者224例(91.8%),显著高于对照组31例(38.3%)(P<0.05);卒中组有不同程度颈动脉硬化斑块形成者186例(76.3%),明显高于对照组13例(16%)(P<0.05)。随着年龄增加,颈动脉斑块及狭窄发生率明显增高。结论高龄人群中颈动脉斑块及狭窄发生率显著较高,颈动脉粥样硬化斑块与缺血性脑卒中的发生密切相关,应用彩色多普勒超声开展脑卒中筛查及建立相应的干预方案,对高危年龄组人群脑卒中的预防及控制有重要意义。更多还原

【Abstract】 Objective To investigate the correlation of carotid atherosclerotic plague and ischemic stroke,and to explore the value of color Doppler ultrasound in application of ischemic stroke. Methods Two hundred and forty-four cases of clinically diagnosed patients with ischemic stroke( stroke group) and 81 volunteers without ischemic stroke( control group) were tested with color Doppler ultrasound. Intima-media thickness( IMT) of CCA and the size,amount of carotid atherosclerotic plague were measured. The incidence of carotid atherosclerotic plague and carotid stenosis happening to the stroke patients among all ages were analyzed. Results The incidence of carotid atherosclerotic plague and stenosis was significantly higher with increasing age. There were 224 cases( 91. 8%) with increased IMT in varying degrees in stroke group. It is significantly higher than that of 31 cases( 38. 3%) campared with that in control group( P < 0.05). In stroke group there were also varying degrees of carotid atherosclerotic plague formation in 186 patients( 76. 3%),significantly higher than that of the 13 cases( 16%) in control group( P < 0. 05). Increasing with age,the carotid atherosclerotic plague and incidence rate were obviously high. Conclusions The carotid atherosclerotic plague and incidence rate are relatively high in the senile age group.Carotid atherosclerotic and ischemic stroke are closely related. Starting stroke screening and intervention programs is important for prevention and control of stroke in high-risk and old people using color Doppler ultrasound.更多还原