【摘要】 目的分析2011年抗菌药物临床应用专项整治活动前后抗菌药物使用情况及变化趋势,为临床合理应用抗菌药物提供参考。方法导出2011年1—8月及2012年1—8月该院HIS系统抗菌药物的品规数、用药金额、用药频度等数据,利用Excel对数据进行统计、分析和总结。结果专项整治活动后,相同时间住院总人数提高7.5%的情况下,抗菌药物使用金额下降21.6%,抗菌药物总DDDs下降31.4%、喹诺酮类抗菌药物DDDs下降15.2%、三、四代头孢菌素的DDDs下降43.2%。特殊使用级抗菌药物DDDs下降66.2%。结论抗菌药物专项整治活动可优化抗菌药物品种、促进抗菌药物临床合理应用并有效遏制细菌耐药。更多还原

【Abstract】 Objective To analyze the use condition and variation trend of antibacterial agents,before and after strict antibiotic restriction policy(SARP),so as to provide reference on how to reasonably use antibiotics in clinic.Methods We exported the data of HIS system antibacterial agents including specification,costs of applied antibiotics,frequency of drug use from January to August of 2011 and 2012 to count,analyze and make conclusion with Excel.Results After strict antibiotic restriction policy,under the condition that total hospitalized patients increased 7.5% in the same period:the cost of applied antibiotics decreased 21.6%;the whole DDDs of antibiotics decreased 31.4%;the DDDs of quinolone antibacterial agents decreased 15.2%;the DDDs of the 3rd and 4th generation cephalosporins decreased 43.2%;the DDDs of antibacterial agents of special usage class decreased 66.2%.Conclusion SARP can optimize the antibacterial agents’ variety,promote the reasonable usage of antibiotics in clinic as well as effectively prevent the drug resistance of bacterium.更多还原