【摘要】 目的:探讨改良式早产儿吸入氧浓度调节方法的临床意义。方法:随机选择需要吸氧的早产儿55例,分为观察组(30例)和对照组(25例),两组均用脉搏血氧仪监测,按照目标脉搏血氧饱和度(SpO2)调节吸入氧浓度(FiO2),稳定半小时后进行血气分析。观察组采用"改进的方法"调节FiO2,每次FiO2变化为0.01;对照组采用常规方法调节FiO2,每次FiO2变化为0.05。测定动脉血氧分压(PaO2),比较两组患儿氧疗调节成功率和调节失败率。结果:观察组氧疗调节成功率(81.3%)显著高于对照组(67.6%),差异有统计学意义(P<0.05);观察组SpO2大于90mmHg的发生率(8.9%)显著低于对照组(21%),差异有统计学意义(P<0.05);观察组SpO2小于50mmHg的发生率与对照组比较,差异无统计学意义(P>0.05)。结论:改良式早产儿吸入氧浓度方法能减少引起氧损伤或氧中毒的发生。更多还原

【Abstract】 Objective:To investigate the clinical significance of "Improved method" in premature infant oxygen therapy. Methods: 55cases of premature infants who needs oxygen therapy divided into observation group(30 cases)and control group(25cases) randomly of two groups were both monitored by pulse oximeter. We adjusted the FiO2(fraction of inspired oxygen)of premature for the target SpO2.the blood gas analysis were done 30 minutes after SpO2stable.The FiO2of observation group were altered by adjustment of 0.01each time with the "Improved method". and the FiO2of control group were altered 0.05 each time as usual. Analysis the PaO2of two groups. Results:The achievement ratio of the PaO2meet the target of observation group(81.3%)was significantly higher than the ratio of control group(67.6%)(P<0.05). The incidence rate of PaO2higher than 90mmHg of observation group(8.9%)was significantly lower than the rate of control group(21.0%)(P<0.05). The difference of the incidence rate of PaO2lower than 50mmHg between two groups was not significantly(P >0.05). Conclusion:The adjustment of FiO2with the "Improved method" in premature infant oxygen therapy could alleviate the hyperoxic lung injury and oxygen toxicity.更多还原