【摘要】 目的:研究甲状腺激素替代治疗对老年甲状腺功能减退患者认知功能的影响。方法:选择90例老年甲状腺功能减退患者为前瞻性研究的对象,在给予甲状腺激素替代治疗后检测外周血甲状腺相关激素FT3、FT4及TSH水平,观察认知功能的变化。结果:患者外周血中FT3、FT4水平及MMSE总评分及定向力、记忆力、注意力和计算力、回忆能力、语言能力评分均呈现治疗后6个月>治疗后3个月>治疗前,TSH水平呈现治疗后6个月<治疗后3个月<治疗前。结论:甲状腺激素替代治疗能够有效改善老年甲状腺功能减退患者的认知功能,具有积极的临床价值。更多还原

【Abstract】 Objective:To study the effect of t thyroid hormone replacement therapy on cognitive function of hypothyroidism patients.Methods:hypothyroidism patients were collected as the object of this prospective study and peripheral blood thyroid hormone FT3, FT4 and TSH level were detected and cognitive function were observed. Results:in the peripheral blood of patients with FT3, FT4 and MMSE total score and orientation, memory, attention and computing power, memory ability, language ability scores showed 6 months after treatment >3 months after treatment>prior treatment; TSH level showed 6 months after treatment < 3 months after treatment< prior treatment. Conclusion: thyroid hormone replacement therapy can effectively improve the cognitive function of elderly hypothyroidism patients.更多还原