【摘要】 介绍了σ-共核蛋白的来源、结构,分析了对帕金森疾病有关键作用的多巴胺合成方面的σ-共核蛋白的调节作用,并探讨了σ-共核蛋白如何发生聚集及发生聚集后可能会造成PD的发生,最后重点讨论了α-共核蛋白引起PD的多巴胺能神经元变性的作用。更多还原

【Abstract】 Firstly,the source,structure of σ-synuclein was introduced,the regulation of σ-synuclein in dopamine synthesis of Parkinson’s disease have a crucial role,then σ-synuclein aggregation and occurrence of PD were discussed.Finally,PD dopamine neurons caused by σ-synuclein was studied.更多还原