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Maastricht标准Ⅲ类心死亡供者供肾移植39例术后早期疗效观察

Early therapeutic efficacy after kidney transplantation from M-Ⅲ type donation after cardiac death in 39 patients

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【作者】 赵亮袁小鹏韩明王小平何晓顺王长希

【Author】 ZHAO Liang *,YUAN Xiao-peng,HAN Ming,WANG Xiao-ping,HE Xiao-shun,WANG Chang-xi.* Department of Urology,Huangpu Hospital,the First Affiliated Hospital,Sun Yat-sen University,Guangzhou 510700,China

【机构】 中山大学附属第一医院黄埔院区泌尿外科中山大学附属第一医院黄埔院区器官移植科中山大学附属第一医院器官移植中心

【摘要】 目的探讨Maastricht标准Ⅲ类(M-Ⅲ类)心死亡供者(DCD)供肾移植术后早期疗效。方法 2010年10月至2012年9月,共39例终末期肾病患者在中山大学附属第一医院接受了M-Ⅲ类DCD供肾移植,予常规免疫抑制治疗,观察术后早期移植肾功能恢复和并发症发生情况。结果共8例发生移植肾功能延迟,发生率为20.5%,2例发生急性排斥反应,余29例移植肾功能均在术后1~2周顺利恢复。结论 M-Ⅲ类DCD供肾移植术后早期移植肾功能延迟发生率较高,无严重并发症,总体疗效较满意。

【Abstract】 Objective To investigate the early therapeutic efficacy after kidney transplantation from M-Ⅲ type donation after cardiac death(DCD).Methods From October 2010 to September 2012,a total of 39 patients with end-stage renal diseases received kidney transplantation from M-Ⅲ type DCD and routine immunosuppressive therapy at the First Affiliated Hospital,Sun Yat-sen University.The postoperative early graft function and complications of recipients were observed.Results Delayed graft function(DGF) was noted in 8 patients(20.5%).Two recipients underwent acute rejection.The others recovered smoothly at 1-2 weeks postoperatively.Conclusion The early therapeutic efficacy after kidney transplantation from M-Ⅲ type DCD was satisfactory in the absence of disastrous complications,though the incidence of DGF was somewhat high.

【基金】 卫生部器官移植科研项目(IHECC07-201009);广东省自然科学基金(S2011010004857);广东省科技计划项目(2010B031600236)
  • 【文献出处】 中华移植杂志(电子版) ,Chinese Journal of Transplantation(Electronic Edition) , 编辑部邮箱 ,2012年04期
  • 【分类号】R699.2
  • 【下载频次】63
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