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Maastricht标准Ⅲ类心死亡供者供肾移植39例术后早期疗效观察
Early therapeutic efficacy after kidney transplantation from M-Ⅲ type donation after cardiac death in 39 patients
【摘要】 目的探讨Maastricht标准Ⅲ类(M-Ⅲ类)心死亡供者(DCD)供肾移植术后早期疗效。方法 2010年10月至2012年9月,共39例终末期肾病患者在中山大学附属第一医院接受了M-Ⅲ类DCD供肾移植,予常规免疫抑制治疗,观察术后早期移植肾功能恢复和并发症发生情况。结果共8例发生移植肾功能延迟,发生率为20.5%,2例发生急性排斥反应,余29例移植肾功能均在术后1~2周顺利恢复。结论 M-Ⅲ类DCD供肾移植术后早期移植肾功能延迟发生率较高,无严重并发症,总体疗效较满意。
【Abstract】 Objective To investigate the early therapeutic efficacy after kidney transplantation from M-Ⅲ type donation after cardiac death(DCD).Methods From October 2010 to September 2012,a total of 39 patients with end-stage renal diseases received kidney transplantation from M-Ⅲ type DCD and routine immunosuppressive therapy at the First Affiliated Hospital,Sun Yat-sen University.The postoperative early graft function and complications of recipients were observed.Results Delayed graft function(DGF) was noted in 8 patients(20.5%).Two recipients underwent acute rejection.The others recovered smoothly at 1-2 weeks postoperatively.Conclusion The early therapeutic efficacy after kidney transplantation from M-Ⅲ type DCD was satisfactory in the absence of disastrous complications,though the incidence of DGF was somewhat high.
【Key words】 Donation after cardiac death; Kidney transplantation; Delayed graft function; Early efficacy;
- 【文献出处】 中华移植杂志(电子版) ,Chinese Journal of Transplantation(Electronic Edition) , 编辑部邮箱 ,2012年04期
- 【分类号】R699.2
- 【下载频次】63