Purpose To compare the value of MR whole body diffusion-weighted imaging (WB-DWI) and single-photon emission computed tomography (SPECT) in detecting bone metastasis of malignant tumor. Materials and Methods Totally 30 patients with malignant tumors were enrolled. All patients underwent WB-DWI and SPECT within 2 weeks. The skeletal system was divided into 8 regions: skull, scapula, sternum/clavicle, ribs, spine, pelvic bone, humerus and femur. The number and the region of the lesions detected by WB-DWI and ...