【摘要】 目的探讨高频超声联合乳管镜检查在乳头溢液疾病中的应用价值。资料与方法61例乳头溢液并乳管扩张患者行乳管镜检查,于镜检术前、术中、术后分别行高频超声检查,观察乳管扩张程度、乳管内膜及乳管形态、走向、乳管内有无肿块等。比较高频超声、超声乳管造影、乳管镜、高频超声联合乳管镜检查对乳头溢液的检出情况。结果 61例(63条乳管)中,乳管内乳头状瘤19条、乳管扩张症22条、乳头状瘤病4条、乳腺癌6条、乳管炎10条,正常乳管2条。高频超声联合乳管镜检查无一条漏误诊,其漏误诊率显著低于高频超声(41.27%,26/63)、超声乳管造影(15.87%,10/63)及乳管镜(9.52%,6/63),差异有统计学意义(χ2=32.76,P<0.01;χ2=10.86,P<0.01;χ2=4.38,P<0.05)。结论高频超声联合纤维乳管内镜检查能有效降低乳管内外病变的漏误诊率,诊断准确性较二者单独应用有很大提高,为乳头溢液的病因诊断、临床手术提供了一种新的诊断和定位模式。更多还原

【Abstract】 Purpose To explore the application of high frequency ultrasound combined with fiber duct endoscopy in galactorrhea.Materials and Methods Sixtyone patients with galactorrhea and expansion duct undertook high-frequency ultrasound examination before,during and after endoscopy surgery.Duct dilatation,endometrial,shape,direction and mass were observed.Results of high-frequency ultrasound,breast ducts contrast-enhanced ultrasound examination,fiber duct endoscopy and high-frequency ultrasound combined with fiber duct endoscopy were compared.Results Of 61 patients (63 breast ducts),19 patients with breast ducts papilloma,22 with breast duct expansion,4 with papilloma disease,6 with breast carcinoma,10 with galactophoritis,and 2 with normal breast ducts.There was no misdiagnosis of high frequency ultrasonography combined with fiber duct endoscopy,which was statistically lower than high-frequency ultrasound (41.27%,26/63),breast ducts contrast-enhanced ultrasound examination (15.87%,10/63),and breast duct endoscopy (9.52%,6/63) alone (χ 2 =32.76,P<0.01;χ 2 =10.86,P<0.01;χ 2 =4.38,P<0.05).Conclusion High-frequency ultrasound combined with fiber duct endoscopy can reduce the rate of missed diagnosis and misdiagnosis for breast lesions,and improve the diagnostic accuracy.It provides a new diagnosis and positioning mode for clinical trial.更多还原