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116例非优质胚胎冻融的临床分析

Analysis of 116 frozen-thawed non-top quality embryo transfer cycles

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【作者】 邓莲马艳萍李永刚高梦莹邓波敖磊相立峰

【Author】 DENG Lian,MA Yan-ping,LI Yong-gang,GAO Meng-yin,AO Lei,XIANG Li-feng.(The Department of Reproduction and Genetics,The First People′s Hospital of Yunnan,Kunming,650032,China)

【机构】 云南省第一人民医院生殖遗传科

【摘要】 目的探讨非优质胚胎在体外受精-胚胎移植中的冷冻价值。方法回顾性分析116例非优质胚胎冷冻移植周期。根据结局分为妊娠组与非妊娠组,比较两组中不同发育速度,均匀度以及碎片比例的胚胎所占比例。结果妊娠组中,卵裂球大小严重不均和碎片比例>20%的胚胎比例显著低于非妊娠组,碎片0-20%的胚胎比例则显著高于非妊娠组。卵裂球大小均匀或明显不均,以及不同发育速度的胚胎比例,二者并无显著差异。结论选择性冷冻非优质胚胎,有助于提高体外受精-胚胎移植的累积妊娠率,改善临床治疗结局。

【Abstract】 Objective:To investigate the clinica vaule of frozen-thawed non-top quality embryo transfer.Methods:One hundred and sixty frozen-thawed cycles were analized retro spectively.all embryos were divided into two groups by the result:pregnancy and unpregnancy.Analysis the difference of composition ratio of the parameter grade of embryo between pregnancy embryo and unpregnancy embryo.Results:In non-top quality embryo,the embryo with serious unequally sized blastomeres or >20% ratio of fragment in pregnancy embryo is lower than in unpregnancy embryo.the embryo with 0-20% ratio of fragment in prignancy embryo is higher than in unpregancy embryo.Conclusion:It will be helpful to select frozen-thawed non-top quality embryo for the result of IVF-ET.

  • 【文献出处】 中国优生与遗传杂志 ,Chinese Journal of Birth Health & Heredity , 编辑部邮箱 ,2012年05期
  • 【分类号】R714.8
  • 【下载频次】68
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