【摘要】 胰岛素受体底物(insulin receptor substrate,IRS)是胰岛素信号传导通路中受体后水平的重要信号蛋白。IRS-1对骨骼生长、骨转换以及骨折愈合等均具有重要作用,为代谢性骨病和骨质疏松的防治提供了新思路。更多还原

【Abstract】 Insulin receptor substrate (IRS ) is an important signaling proteins in insulin signal transduction pathways. IRS-1 plays an important role in skeletal growth, bone turnover and bone fracture healing. It may be a new point for the prevention and treatment of metabolic bone disease and osteoporosis.更多还原