【摘要】 目的:观察蝮蛇咬伤患者凝血功能的变化情况和自制中药(外用蛇肿散及内服蛇毒消)对其的影响。方法:把93例蝮蛇咬伤患者,随机分为两个组,治疗组47例,对照组46例,均给予常规治疗,治疗组加服中药蛇毒消,均以7天为1个疗程。分别于治疗前及治疗后1天、3天、7天抽血观察并比较两组患者凝血功能指标(PT、TT、APTT、FIB、DD、PLT)的变化情况。结果:入院治疗前和治疗1天后两组凝血功能变化无明显差异性;治疗3天后,两组FIB、TT比较具有明显差异性(分别为P<0.05,P<0.05),其他指标两组比较无明显差异性;治疗7天后,两组指标FIB、TT比较具有明显差异性(分别为P<0.01,P<0.05),其他指标两组比较无明显差异性。结论:蝮蛇咬伤患者的凝血功能指标FIB、TT变化明显,中药能明显减轻蝮蛇咬伤患者凝血功能异常。更多还原

【Abstract】 Objective:To observe of coagulation function in Agkistrodon halys snakebites and to analyze effect of self-made Chinese medicine treatment for snakebite on coagulation function in Agkistrodon halys snakebites.Methods:93 patients with Agkistrodon halys snakebite were randomly divided into two groups.46 patients in the control group were treated with conventional therapy and 47 patients in the trial group with conventional therapy and self-made Chinese medicine Treatment for snakebite.The changes of coagulation functions(including PT,TT,APTT,FIB,DD and PLT)before treatment and 1,3,7 days later were compared between the two groups.Results:The coagulation functions(including PT,TT,APTT,FIB,DD and PLT)have no statistically significant difference between the two groups before treatment and 1 day later,but FIB and TT have statistically significant difference after 3,7 days treatment.Conclusion:The changes of FIB and TT are obvious in Agkistrodon halys snakebites and the abnormal coagulation function after Agkistrodon halys bited can improved by self-made Chinese medicine treatment.更多还原