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不同血液净化方式对尿毒症患者甲状旁腺激素的影响
The Effect of Different Modes of Blood Purification to Parathyroid Hormone in Uremia Patients
【摘要】 目的:研究血液透析(HD)、血液透析滤过(HDF)对尿毒症患者血清甲状旁腺激素(PTH)的清除情况。方法:选择患者64例,随机分为两组,每组32例。A组采用每周HD治疗3次;B组采用每周1次HD治疗、2次HDF治疗。治疗6个月,观察PTH的变化。结果:治疗6个月后,A组血清PTH无明显下降,B组血清PTH下降明显,两组治疗前后PTH比较差异有统计学意义(P<0.05)。结论:两种血液净化方式均能清除PTH,但采用每周1次HD、2次HDF治疗效果佳,对PTH清除效果好。
【Abstract】 Objective:Study the serum parathyroid hormone(PTH)clearance by hemodialysis(HD),hemodiafiltration(HDF) in uremic patients.Methods:64 cases of patients were divided into 2 groups randomly,32 cases in each group.Patients in group A were treated with HD 3 times a week.Patients in group B were treated with HD 1 time and HDF 2 times a week.Observe changes of PTH after treatment for 6 months.Results:After treatment of 6 months,PTH has no obviously decline in group A while decreased obviously in group B.The change of PTH was significantly different before and after treatment in two groups(P<0.05).Conclusion:The two ways of blood purification are both able to remove PTH,and the treatment of 1 time with HD and 2 times with HDF a week was better in effect of PTH removement.
【Key words】 Parathyroid hormone; Blood dialysis; Hemodialysis filtration;
- 【文献出处】 中国医学创新 ,Medical Innovation of China , 编辑部邮箱 ,2012年18期
- 【分类号】R692.5
- 【被引频次】5
- 【下载频次】36