【摘要】 目的利用动脉硬化检测仪VP-1000(BP203RPEII型,PVW/AB1型)观察不同剂量立普妥对动脉硬化的影响。方法将符合标准的261例患者临床随机分为两组,试验一组口服立普妥10mg/d(n=131),试验二组口服立普妥20mg/d(n=130),疗程为12个月,应用全自动动脉硬化测定仪对患者治疗前后行PWV测定,观察治疗前后PWV指标。结果两组药物治疗12个月后与治疗前组内比较动脉硬化指数有明显改善(P<0.05),两组组间比较动脉硬化指数无统计学意义(P>0.05)。结论每天口服立普妥10mg即可达到较好的治疗效果,且安全、有效。更多还原

【Abstract】 Objective Using detector VP-1000(BP203RPEII type,PVW/AB1 type) to observe the influence of atherosclerosis along with the change of lipitor doses.Methods Divide the standard 261 patients into two groups with clinical randomly.Group 1:oral lipitor 10 mg/d(n = 131) and Group 2:oral lipitor 20 mg/d(n = 130).The treatment both were 12 months.Application of automatic atherosclerosis locator to set out PWV before and after the treatment.Watch the change of PWV.Results The treatment for 12 months indeed obviously had improved the arteriosclerosis index(P<0.05).There was no statistically significant for the comparison between group 1 and group 2(P>0.05).Conclusion Oral lipitor 10 mg everyday can achieve a better treatment effect,safty and effectively.更多还原