【摘要】 目的调查湖北省自1950年后的首起布鲁菌病暴发疫情的感染来源和传播的危险因素,2011年暴发发生在湖北省孝感市大悟县。方法采用病例搜索、流行病学调查和回顾性病例对照研究。结果本起人间布病暴发有同村9名病例,其中疑似病例1例和实验室确诊病例8例,其中2例血培养出布鲁氏菌羊种3型。病例对照研究显示接触羊的OR=7(1.02～52.59),主要接触方式为对引入羊群进行饲养和清扫羊圈。同村现存羊检测布鲁菌血清抗体阳性。结论引入羊群的饲养是发生布鲁氏菌病疫情的主要因素,应加强对高危人群的监测和对羊群的检疫。更多还原

【Abstract】 To clarify the infection source and risk factors of transmission in a brucellosis outbreak in Dawu County,Xiaogan City during the periods from October 2010 to August 2011 which was the first outbreak in Hubei Province since 1950s,we conducted case searching,epidemiologic investigation and retrospective case-control study.There were 9 brucellosis patients in the same village in this outbreak,including 1 suspected case and 8 laboratory-confirmed cases.Two strains of B.melitensis biovar 3 were cultured in the blood of 2 confirmed cases.The case-control study showed that OR value of contacting sheep was 7(1.02-52.59)and the ways of contacting were feeding the introduced sheep and cleaning the sheepfold.The current goats in the same village were detected positive for Brucella antibody.Because the feeding of introduced goats flock was the source of this brucellosis outbreak,we should strengthen the surveillance of the population at high risk and quarantine of the sheep or goats flock.更多还原