【摘要】 目的观察帕利哌酮联合无抽搐电休治疗(MECT)对难治精神分裂症患者认知功能的影响。方法 30例精神分裂症患者进行帕利哌酮联合MECT治疗,治疗前后进行威斯康星卡片分类(WCST)、连线试验A和B、数字广度、数字符号和临床记忆量表(CMS)检测。结果治疗后,患者连线试验A、B完成时间较治疗前缩短(P<0.05),WCST测试、数字符号、数字广度及CMS治疗前后均无显著性差异。结论帕利哌酮联合MECT治疗能改善难治性精神分裂症患者的记忆功能及注意力功能。更多还原

【Abstract】 Objective To investigate the effect of paliperidone extended-release combined with modified electric convulsive therapy(MECT) on cognitive function in patients with refractory schizophrenia.Methods 30 patients were reviewed with the Wisconsin Card Sorting Test(WCST),the Trail Making Test A and B,Digit Span Test(DST),Digit Symbol Substitution Test(DSST) and the Clinical Memory Scale(CMS).Results The time shortened after treatment in the Trail Making Test A and B(P<0.05).There was no significant difference before and after the treatment in the other tests.Conclusion Paliperidone combined with modified electric convulsive therapy may inmprove the memory and attention in schizophrenics.更多还原