【摘要】 目的研究超声及血清学检查在胎儿巨细胞病毒感染预测中的应用价值。方法选择2010年10月-2011年9月医院就诊及住院的孕妇168例,其中先天性巨细胞病毒感染胎儿26例,对孕妇每2周进行1次超声扫描,监测胎儿的发育情况;另采用酶联免疫吸附法(ELISA)对血清中特异性的CMV-IgM进行检测;比较分析超声及血清学检测异常的发生例数。结果胎儿巨细胞病毒感染的发生率为15.48%;超声发现异常9例,异常率为34.62%,血清中CMV-IgM阳性14例,阳性率为53.85%,差异有统计学意义(P<0.05)。结论超声及血清学检测在胎儿巨细胞病毒感染的预测中均具有重要的作用,在临床中,可根据孕妇的具体情况,综合多方面检查的结果进行确诊。更多还原

【Abstract】 OBJECTIVE To probe into the application value of ultrasound and serological testing in prediction of fetal cytomegalovirus infections.METHODS From Oct 2010 to Sep 2011,a total of 168 cases of hospitalized pregnant women were selected,including 26 cases with fetus infected with congenital cytomegalovirus;ultrasound scans once every 2 weeks for pregnant women was performed,the fetal development was monitored;while enzyme-linked immunosorbent assay(ELISA) was adopted for the detection of serum CMV-IgM-specific;the abnormalities detected with ultrasound and serological testing were compared and analyzed.RESULTS The incidence of fetal cytomegalovirus infections was 15.48%,there were 9 cases with abnormalities with ultrasound,the abnormal rate was 34.62%,there were 14 cases with serum CMV-IgM positive,the positive rate was 53.85%,the difference was statistically significant(P<0.05).CONCLUSION Ultrasound and serological testing plays an important role in the prediction of fetal cytomegalovirus infections;as in the clinical practice,the results of multiple examinations are integrated to confirm according to the specific circumstances of pregnant women.更多还原