【摘要】 随着药物筛选技术的不断发展,新的筛选途径和技术不断涌现,使得药物筛选朝着快速、高效、高通量等方面不断发展。微流控分析技术具有的分析微型化、高通量化、可集成化和良好的生物相容性等特点,为天然产物活性成分的筛选提供了新的方法和技术平台,该文介绍了用于天然产物活性成分的多种筛选方法,重点综述了与细胞培养相结合的微流控芯片筛选技术及其特点,微流控芯片筛选技术平台的构成,以及其在天然产物活性成分筛选中的应用。更多还原

【Abstract】 With the constant development of the drug screening technology,new screening methods and techniques have came to the fore,driving drug screening to grow rapidly and efficiently with a high throughput.Characterized by micro-scale analysis,high throughput,inheritability and good biocompatibility,the micro-fluidic analytical technology provides a new method and technical platform for screening active ingredients from natural products.This essay introduces multiple methods used for screening active ingredients from natural products and focuses on the micro-fluidic chip screening technology combined with cell culture and its characteristics,the composition of the platform of the micro-fluidic chip screening technology and its application in screening active ingredients from natural products.更多还原