【摘要】 目的:了解全国野生和栽培甘草的甘草酸含量范围,初步寻找影响甘草酸含量的相关因素。方法:采用HPLC测定收集于全国9省区37个旗县165份野生甘草和1 013份栽培甘草的甘草酸含量,分析产地、药用部位、栽培年限、土壤类型与质地对甘草酸含量的影响。结果与结论:野生甘草的甘草酸质量分数平均为(4.43±1.32)%,而栽培甘草的甘草酸质量分数平均为(1.51±0.49)%,低于2010年版《中国药典》的最低标准。不同产地野生和栽培甘草的甘草酸含量均存在显著差异(P<0.05),野生甘草中,根和根茎的甘草酸含量不存在显著差异,一至四年生阶段栽培甘草的甘草酸含量不存在显著差异,五年生后甘草酸含量快速增高,栽培地土壤类型和质地对甘草酸含量的影响未达到显著水平。更多还原

【Abstract】 Objective: In order to understand the glycyrrhizin content range in the wild and cultivated Glycyrrhiza uralensis in China and to find the related influencing factors of glycyrrhizin content.Method: The glycyrrhizin content of 165 wild and 1 013 cultivated G.uralensis samples from 37 countries in 9 provinces was determined by HPLC,and the effects of the producing region,medicinal parts,cultivation years,soil type and texture on the glycyrrhizin content were analyzed.Result and Conclusion: The average glycyrrhizin content was(4.43±1.32)% in the wild G.uralensis population,and(1.51±0.49)% in the cultivated and the glycyrrhizin content in the cultivated was less than the minimum sandards in the Chinese Pharmacopoeia.The glycyrrhizin content was significant different in the wild and cultivated G.uralensis in different producing regions,respectively.The glycyrrhizin content in roots and rhizome of the wild G.uralensis had no significant difference,it had no significant difference in the cultivated G.uralensis from 1 to 4 years and it increased rapidly after 5 years,and the effects of the soil types and texture on it were significant.更多还原