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湖北羊蹄甲的化学成分研究

The Chemical Constituents of Bauhinia glauca(Wall. ex Benth.) Benth. subsp. hupehana(Craib) T.Chen

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【作者】 白明安图任凤霞杨郁张杨屈爱桃赵毅民

【Author】 BAIMING An-tu1,REN Feng-xia2,YANG Yu2,ZHANG Yang2,QU Ai-tao,ZHAO Yi-min2(1.Inner Mongolia Medical College,Hohhot 010059,China;2.Institute of Pharmacology and Toxicology,Academy of Military Medical Sciences,Beijing 100850,China)

【机构】 内蒙古医学院军事医学科学院毒物药物研究所

【摘要】 目的研究湖北羊蹄甲[Bauhinia glauca(Wall.ex Benth.)Benth.subsp.hupehana(Craib)T.Chen]茎叶的化学成分。方法植物材料经丙酮冷浸提取,色谱法分离化学成分,根据其波谱数据鉴定化合物结构。结果分离鉴定了5个化合物,分别为4-甲氧基新异甘草苷(1),bauhiniasin(2),硫黄菊素(3),异甘草素(4),4’-甲氧基新甘草苷(5)。结论其中化合物1为新天然产物,化合物2,4为本植物首次分离,化合物3,5为本属首次分离。

【Abstract】 OBJECTIVE To study the chemical constituents of the stem and leaves of Bauhinia glauca(Wall.ex Benth.) Benth.subsp.hupehana(Craib) T.Chen.METHODS The plant material was extracted with acetone at room temperature.The chemical constituents were isolated by chromatographic methods and their structures were identified by spectroscopic analysis.RESULTS Five compounds were obtained and identified as(2′,4′-dihydroxy-4-methoxychalcone)-4′-β-D-glucoside(1),bauhiniasin(2),sulfuretin(3),isoliquiritigenin(4),and 4′-methylglucoliquiritigenin(5).CONCLUSION Compound 1 is a new natural product,and this is the first time to find compounds 2 and 4 in this plant and compounds 3 and 5 in this genus.

  • 【文献出处】 中国药学杂志 ,Chinese Pharmaceutical Journal , 编辑部邮箱 ,2012年22期
  • 【分类号】R284
  • 【被引频次】2
  • 【下载频次】184
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