【摘要】 目的:探讨临床药师在异基因外周血干细胞移植(allo-PBSCT)患者临床治疗中发挥的作用。方法:通过临床药师对2例allo-PBSCT患者实施药学监护,参与制订治疗方案,全程参与临床查房、病例讨论,对患者进行药学监护和用药教育。结果:A患者allo-PBSCT术后第11天,血常规提示造血重建;期间监测巨细胞病毒(HCMV-DNA)结果呈阴性;骨髓细胞学示骨髓增生明显活跃;患者生命征平稳,无发热等不适反应。B患者allo-PBSCT术后第11天,血常规提示造血重建。期间监测HCMV-DNA结果呈阴性;骨髓细胞学示粒系增生,红系增生低下;患者无发热、皮疹等移植物抗宿主病(GVHD)表现。结论:临床药师通过参与allo-PBSCT患者的药学监护,协同医师制订用药方案,可提高医师、护士和患者对临床药师的认可,减少药品不良反应,提高药物治疗效果,体现临床药师的价值。更多还原

【Abstract】 OBJECTIVE:To study the role of clinical pharmacists in the treatment for patients with allogeneic peripheral blood stem cell transplantation(allo-PBSCT).METHODS:Clinical pharmacists provided pharmaceutical care for 2 cases of allo-PBSCT,participated in the formulation of therapeutic plan,ward-round and case discussion,and carried out pharmaceutical care and medication education.RESULTS:11 days after allo-PBSCT,routine blood test of patient A reminded hematopoietic reconstruction;HCMV-DNA was negative;bone marrow inspection showed active bone marrow hyperplasia;the vital signs of patients were stable without fever and other ADR.11 days after allo-PBSCT,routine blood test of patient B reminded hematopoietic reconstruction;HCMV-DNA was negative;bone marrow inspection showed myeloid cell hyperplasia and low erythroid cell hyperplasia;no fever,erythra and other GVHD manifestation were found.CONCLUSION:Through clinical pharmacists participate in pharmaceutical care for allo-PBSCT patients,and collaborate with doctors on medical plan to improve the acceptance of doctors,nurses and patients for clinical pharmacists and realize the value of them.更多还原