【摘要】 目的:了解蚌埠地区抗菌药物致不良反应(ADR)的发生情况。方法:对2009-2010年蚌埠地区上报的抗菌药物致ADR报告,按性别、年龄、给药途径、药品类别、ADR累及器官或系统及临床表现等进行统计、分析。结果:ADR涉及的抗菌药物共107种,2791例/次,发生频次以头孢菌素类居首位(占31.31%),其次为喹诺酮类和青霉素类;主要的ADR类型为皮肤及其附件损害,占40.58%;严重ADR11例。结论:临床应规范抗菌药物的临床应用,以减少其ADR的发生率。更多还原

【Abstract】 OBJECTIVE:To investigate the situation of antibiotics-induced adverse drug reactions(ADR) in Bengbu area.METHODS:According to gender,age,route of administration,drug category,organs or systems involved in ADR,clinical manifestations,and so on,reports of antibiotics-induced drug adverse reactions reported in Bengbu from 2009 to 2010 were analyzed statistically.RESULTS:107 antibiotics were involved in ADR for 2 791 times.ADR most occurred in cephalosporin antibiotics(31.31%),followed by quinolones and penicillins.Primary ADR type was lesion of skin and its appendents,which accounted for 40.58% of the total.11 cases suffered from serious ADR.CONCLUSIONS:Clinical application of antibiotics should be standardized to reduce the incidence of ADR.更多还原