【摘要】 目的观察宫颈电环切除术(LEEP术)联合保妇康栓治疗宫颈上皮内瘤变(CIN)合并高危型人乳头瘤病毒(HPV)持续感染的疗效。方法 158例病例随机分为两组,对照组79例,治疗组79例。治疗组患者在LEEP术后于阴道内放置保妇康栓,对照组未放置任何药物。观察两组患者宫颈创面愈合时间、术后并发症的发生情况、CIN消退及高危型HPV持续感染的情况。结果两组患者宫颈创面愈合时间、并发症发生情况比较差异无统计学意义(P>0.05);而CIN消退差异有统计学意义(P<0.05);高危型HPV持续感染率差异有统计学意义(P<0.01)。结论 LEEP术联合保妇康栓治疗CIN合并高危型HPV持续感染疗效满意,是较为理想的方法。更多还原

【Abstract】 Objective To observe the effect of the loop electrosurgical excision procedure(LEEP) combined with Baofukang suppository in cervical intraepithelial neoplasia(CIN) and persistent infection of high risk human papillomavirus(HR-HPV).Methods 158 patients were randomly divided into two groups: control group(n=79) and treatment group(n=79).Baofukang suppository was placed into the vagina after LEEP in the treatment group.The healing time,post operative complications,the regression rate of CIN and persistent infection of HR-HPV were observed in the two groups.Results There were no significant differences in the healing time and post operative complications(P>0.05),but there were significant differences in the regression rate of CIN and persistent infection rate of HR-HPV between two groups(P<0.05 and P<0.01 respectively).Conclusion LEEP combined with Baofukang suppository is an effective method for treatment of CIN and persistent infection of HR-HPV with satisfactory effects.更多还原