【摘要】 目的探讨代谢综合征(MS)与颈动脉中膜厚度的相关性。方法选择2007年5月～2011年3月于本院就诊并被诊断为代谢综合征的95例患者作为研究组,同时严格按照随机化的原则选择95例健康人作为对照组,应用血管彩色超声对两组人群的颈动脉内中膜厚度(IMT)进行测定,对测定结果进行相关性分析。结果研究组IMT厚度较对照组呈明显增加趋势,差异有统计学意义(P<0.05);研究组的颈动脉粥样硬化斑块形成率为89.5%,对照组为58.9%,两组间情况比较,差异有统计学意义(P<0.05);研究组颈动脉中重度狭窄率为47.6%,对照组为11.9%,差异有统计学意义(P<0.05);血管闭塞率研究组为50.0%,对照组为0,差异有统计学意义(P<0.05)。结论患有代谢综合征的人群其颈动脉中膜厚度明显高于健康人群,可见,代谢综合征可促进颈动脉粥样硬化的发展。更多还原

【Abstract】 Objective To investigate the correlation between metabolic syndrome(MS) and intima-media thickness.Methods Ninety-five cases of patients were selected in our hospital who was diagnosed with metabolic syndrome from May 2007 to March 2011 as a research group,95 cases of healthy people were selected as control group,use color doppler ultrasound to mensurate the intima-media thickness of people in two groups.The correlation analysis of determination results were made.Results The IMT thickness of research group showed a significantly increasing trend than control group,the differ ence was statistically significant(P < 0.05);the formation rate of carotid atherosclerotic plaque in research group was 89.5%,and it was 58.9% in control group,the difference was statistically significant(P < 0.05);the rate of carotid artery severe stenosis in research group was 47.6%,and it was 11.9% in control group,the difference was statistically significant(P < 0.05);the rate of vascular occlusion in research group was 50.0%,and the control group was 0,the difference was sta tistically significant(P < 0.05).Conclusion The intima-media thickness in population with metabolic syndrome are significantly higher than the healthy population,it is thus clear that metabolic syndrome can promote the development of carotid atherosclerosis.更多还原