【摘要】 目的观察血浆置换联合血浆灌流治疗肝衰竭患者不良反应的发生。方法序贯应用血浆置换联合血浆灌流治疗68例慢加急性肝衰竭患者共146例次,观察并总结治疗中及治疗后24h内不良反应发生情况。结果治疗过程中与治疗后24h内总体不良反应发生率低(21.2%),以低钙致口唇麻木最常见,无严重不良反应发生,所有不良反应经对症治疗均缓解,无一例患者因不良反应导致死亡。结论血浆置换联合血浆灌流治疗肝衰竭不良反应发生少,是治疗肝衰竭安全有效的方法。更多还原

【Abstract】 Objective To observe the adverse reactions of combination therapy of plasma exchange (PE) and plasma perfusion (PP) in patients with liver failure. Methods There were totally 146 person-times including 64 patients who received a combination therapy of PE and PP, and patients with acute liver failure. The occurrence condition of adverse reactions during treatment and in 24 hours after treatment were closely observed and summarized. Results The total adverse reaction rate during treatment and in 24 hours after treatment was lower of 21.2%, with the most common of numb lip caused by low calcium, no severe adverse reaction occured. All the bad reaction symptomatic were alleviated with the symptomatic treatment, no case died of adverse reaction. Conclusion The combination therapy of PE and PP for the patients with liver failure is a safe therapeautic method for the treatment of liver failure with the low adverse reaction.更多还原