【摘要】 目的探讨他汀类药物对骨质疏松症骨密度及骨折危险性的影响。方法随机选择167例符合高脂血症和骨质疏松症诊断标准的患者服用他汀类药物,并与对照组比较,每6个月测定一次骨密度,连续观察18个月。结果实验组服药12个月后骨密度显著提高,与对照组比较,差异有统计学意义(P<0.05);骨折发生率为6.6%,与对照组比较,差异有统计学意义(P<0.05)。结论他汀类药物能提高骨质疏松症患者的骨密度,降低骨折的危险性,有可能成为新的有效的治疗骨质疏松的药物。更多还原

【Abstract】 Objective To investigate the influence of statins drugs on bone density and fracture risk.Methods One hundred and sixty seven patients with hyperlipidemia and osteoporosis were randomly selected as experimental group and given statins drugs,and compared with control group.Bone density was measured once every six-month and observed about 18 months continuousely.Results The bone density of experimental group increased remarkably after taking statins drugs about 12 months,which had significant difference compared with control group(P<0.05).The incidence rate of bone fracture was 6.6%,which also had significant difference compared with control group(P<0.05).Conclusion The statins drugs can increase the density of osteoporosis and reduce the risk of bone fracture;it may become a new effective treatment for osteoporosis.更多还原