艾迪注射液联合同步放化疗治疗食管癌的临床观察

【摘要】 目的:观察艾迪注射液联合同步放化疗治疗食管癌的疗效和不良反应。方法:收治食管癌患者62例,随机分为两组,艾迪注射液组(A组)31例采用艾迪注射液联合同步放化疗的方法;对照组(B组)31例采用单纯同步放化疗的方法。艾迪注射液组中艾迪注射液80ml+NS400ml,d1～d14/周期。治疗期间每周观察骨髓抑制、放射性食管炎、消化道反应等不良反应。同步放化疗结束后2周观察患者机能状态及免疫功能。放化疗后3个月、12个月评价有效率(CR+PR)。结果:艾迪注射液组和对照组总有效率分别为93.55%和87.10%(P>0.05)。对照组不良反应大于艾迪注射液组,骨髓抑制、胃肠道反应及放射性食管炎发生率差异有显著性(P<0.01)。结论:艾迪注射液联合同步放化疗治疗食管癌能减轻放化疗的不良反应,提高肿瘤患者的生存质量,并能提高有效率。更多还原

【Abstract】 Objective:to observe the eddy injection joint chemoradiation treatment in patients with cancer of the esophagus efficacy and side effects.Methods:the March 2008～2009 12 menstrual pathology esophageal for 62 cases of patients,randomly divided into two groups:eddy injection group(group A)31 cases by the eddy injection chemoradiation joint the method;The control group(group B)31 cases by the simple method of chemoradiation alone.Eddy injection group eddy injection 80 ml+NS 400ml,d1～d14/cycle.A week during treatment of bone marrow suppression,observe radioactive esophagitis,gastrointestinal reaction and other side effects.Two weeks after the chemoradiation observe patients functional status and immune function.Radiation and chemotherapy after 3 months,12 months evaluation efficient(CR+PR).Results:eddy injection group and control group total effectiveness 93.55% and 87.10%,respectively(P>005).The control group side effects than eddy injection group, bone marrow,suppression,gastrointestinal reaction and radioactive esophagitis rate(P<0.01).Conclusion:eddy injection joint chemoradiation treatment can reduce esophageal the adverse reaction of radiation and chemotherapy,improve the quality of life of patients with cancer,and can improve the efficient,deserves further study confirmed.更多还原