帕瑞昔布钠对乳腺癌根治术患者舒芬太尼自控静脉镇痛效果的影响

【摘要】 目的:探究帕瑞昔布钠在乳腺癌根治术患者的舒芬太尼自控静脉镇痛中的临床应用价值。方法:采用前瞻性开放研究,收治拟行乳癌根治术的患者80例,随机分为两组,分别用帕瑞昔布钠和安慰剂进行治疗,比较两组的情况。结果:分别比较两组术后2、12、24小时的VAS评分及Ramsay评分,2及12小时VAS差异有统计学意义(t1=16.76,t2=3.82,P<0.05);术后2小时Ramsay评分差异有统计学意义(t=8.36,P<0.05)。结论:将帕瑞昔布钠应用于乳腺癌根治术患者的舒芬太尼自控静脉镇痛过程中,可以提高镇静、镇痛的质量,效果满意,因此其应用面将会越来越广。更多还原

【Abstract】 Objective:To investigate the clinical significance of parecoxib on sufentanil self-controlled vein analgesic effect in Breast cancer patients after radical mastectomy.Methods:With the prospective open study,80 breast cancer patients who would accepted radical mastectomy were collected from January 2009 to February 2011 in our hospital,and put them into two groups as study group and control group randomly,respectively for parecoxib and placebo treatment,compared the difference between the two groups.Results:The two groups were compared with the VAS score and the Ramsay score of 2 hours,12 hours,and 24 hours after radical mastectomy.There were significant differences between two group in two hours and 12 hours of the VAS(t1=3.82,t2=16.76,P<0.05);And were significant differences in two hours of Ramsay score(t=8.36,P<0.05).Conclusion:It show parecoxib obvious advantages in applying sufentanil self-controlled vein analgesic effect which is worthy of clinical promotion or can be recognized as a prior choice.更多还原