【摘要】 目的探讨醋酸白及碘试验肉眼观察法在宫颈癌筛查中的意义。方法 2008年3月至10月应用醋酸白及碘试验肉眼观察法(VIA/VILI)对华北地区6县市(北京大兴区、天津大港区、河北赤城和曲周、山西襄垣和沁县)6地区部分生育年龄农村妇女进行宫颈癌筛查,对阳性者行阴道镜检查,如异常取活检病理学检查,确诊病变者依据早诊早治技术方案进行治疗。结果 6地区共筛查12208例,大兴、大港、赤城、曲周、襄垣、沁县:VIA/VILI阳性率分别为11.50%、17.95%、21.88%、6.19%、2.95%、6.11%;阴道镜检查的活检率分别为80.43%、83.33%、8.26%、48.00%、100.00%、74.40%;活检病例中宫颈高度以上病变所占比例分别为6.49%、15.67%、18.42%、1.67%、18.33%、21.51%;VIA/VILI对宫颈高度以上病变检出率分别为5.22%、13.06%、1.52%、0.80%、18.33%、16.00%。结论不同地区醋酸白及碘试验肉眼观察法在应用和推广中存在一定的局限性,应予以重视。更多还原

【Abstract】 Objective To evaluate the visual inspection with acetic acid and Lugol’s iodine as cervical cancer screening tools.Methods In the six rural areas of north China,visual inspection with acetic acid and Lugol’s iodine was applied in reproductive women to screen cervical cancer in 2008.Once the result was positive,colposcopy was followed.If the colposcopy was abnormal,biopsy was carried.According to the pathological result,appropriate treatment followed.Results In six areas,12208 women were recruited.The positive rate of VIA/VILI was 11.50%,17.95%,21.88%,6.19%,2.95%,6.11%,respectively.For colposcopy cases,the rate of biopsy is 80.43%,83.33%,8.26%,48.00%,100.00%,74.40%,respectively.Among them,the diagnosis rate of high grade cervical intraepithelial neoplasia is 6.49%,15.67%,18.42%,1.67%,18.33% and 21.51%,respectively.For high grade lesion,the diagnosis rate of VIA/VILI is 5.22%,13.06%,1.52%,0.80%,18.33% and 16.00%,respectively.Conclusion In different areas,the technology of VIA/VILI and colposcopy is different.It is a serious problem in VIA/VILI clinical practice.We should pay more attention to the clinical training and quality control;it is the most important thing in the cervical screen program.更多还原