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新药物对奶牛感染性蹄病动物模型临床疗效试验

Curative Effect of New Medicament for Treating Animal Model as Infective Foot Rot of Cattle Dairy

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【作者】 廖党金谢晶李江凌曹冶文豪赵素君田浪李红

【Author】 LIAO Dang-jin,XIE Jing,LI Jiang-ling,CAO Ye,WEN Hao,ZHAO Su-jun,TIAN Lang,LI Hong(Sichuan Academy of Animal Science,Chengdu 610066)

【机构】 四川省畜牧科学研究院

【摘要】 为探索治疗奶牛感染性蹄病的新药物,以患蹄病的绵羊为奶牛感染性蹄病的动物模型进行临床治疗试验。试验药物是针对奶牛感染性蹄病病原特点研制的5种配方,即配方Ⅰ~配方Ⅴ。选择自然感染蹄病的绵羊50只,随机分为7个组,各组羊只分别为配方Ⅰ组6只、配方Ⅱ组7只、配方Ⅲ组10只、配方Ⅳ组9只、配方Ⅴ组8只、药物对照组5只、空白对照组5只。结果表明,在本试验药物组中,临床疗效依次为配方Ⅴ>配方Ⅲ>配方Ⅱ>配方Ⅳ>配方Ⅰ,配方Ⅴ的效果最佳,有效率和治愈率分别达100%、88.9%。综合比较,本试验药物的治疗效果要优于传统药物。

【Abstract】 For exploration of a new medicament for treatment of infective foot rot of cattle dairy,50 foot rot sheep as a model of cattle dairy were random divided into seven groups,group Ⅰ of 6 foot rot sheep for new medicament Ⅰ,group Ⅱ of 7 foot rot sheep for new medicament Ⅱ which were aiming at the pathogenic bacteria of cattle dairy foot rot,group Ⅲ of 10 foot rot sheep for new medicament Ⅲ,group IV of 9 foot rot sheep for new medicament IV,group V of 5 foot rot sheep as medicament controlling and group V of 5 foot rot sheep as controlling.The results were that curative effect order was medicament Ⅴ,medicament Ⅲ,medicament Ⅱ,medicament Ⅳ and medicament Ⅰ.The compositive comparison displayed that the medicament Ⅴ and the medicament Ⅱ were better than medicament controlling.

【关键词】 动物模型奶牛感染性蹄病
【Key words】 Animal modelCattle dairyInfective foot rot
【基金】 国家支撑计划(2006BAD04A17);四川省支撑计划项目(2010NZ0106);四川省畜牧科学研究院基金
  • 【文献出处】 中国奶牛 ,China Dairy Cattle , 编辑部邮箱 ,2012年19期
  • 【分类号】S858.23
  • 【被引频次】2
  • 【下载频次】50
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