【摘要】 目的探讨胆囊癌超声造影征象特征及临床应用价值。方法对384例胆囊占位性病变进行超声造影筛查,观察造影征象特征,并将诊断结果与病理相比较。结果 (1)胆囊癌超声造影特征性表现动脉早期快速不均质增强,外形不规则,胆囊壁增厚不规则突起,部分呈断续现象,病灶基底部增宽与胆囊壁相连,动脉中晚期或门脉早期快速廓清,呈"快进快退"表象。(2)对比胆囊良恶性占位超声造影特征性表象有统计学意义(P<0.05)。(3)与病理比较超声造影对胆囊癌诊断的敏感度、特异度及准确率分别为96.6%(28/29)、99.4%(353/355)、99.2%(381/384)。结论超声造影对提高胆囊癌诊断与鉴别诊断具有较高的临床价值。更多还原

【Abstract】 Objective To explore the clinical value and charateristics of contrast-enhanced ultrasound(CEUS)in diagnosis of gallbladder carcinoma.Methods 384 patients with benign and malignant gallbladder disease were examined by CEUS.The characteristics of CEUS were analyzed and compared with pathological examination.Results(1) The CEUS patterns of Gallbladder carcinomas showed quick and heterogeneous hyper-enhancement at the early arterial phases.The CEUS shape of the gallbladder carcinomas were irregular.The wall of gallbladder was irregular thicken and interrupted by the mass.The basement of lesions were wide and connected with the gallbladder wall.Almost all the gallbladder carcinomas showed washout from hyper-enhancement to hypo-enhancement quickly after contrast agent administration.(2)It was significant different between benign and malignant gallbladder diseases of CEUS characteristics (P<0.05).(3)Compared with pathological examination,the sensitivity,specificity and accuracy of CEUS in gallbladder carcinomas diagnosis was 96.6%(28/29),99.4%(353/355),99.2%(381/384)respectively.Conclusions CEUS has an important clinical value in diagnosis of gallbladder carcinoma.更多还原