【摘要】 目的探讨原发性蝶窦颅咽管瘤的临床特点,以提高诊断水平。方法回顾性分析2例原发性蝶窦颅咽管瘤患者的临床资料并结合文献复习。结果 2例患者因头痛、眼眶疼痛就诊,MRI显示蝶窦内囊性占位,增强未见强化;术中肿瘤呈囊性,囊内为棕黄色黏稠液体,其中1例内可见胆固醇结晶。术后随访症状缓解,未见肿瘤复发。结论原发性蝶窦颅咽管瘤极为少见,考虑来源于胚胎期Rathke’s囊移行过程中残留的颅咽管组织细胞成份,诊断上需与蝶窦内常见囊性病变相鉴别,病检是唯一确诊手段,首选手术治疗。更多还原

【Abstract】 Objective To explore the clinical features of primary sphenoid sinus craniopharyngioma to improve the diagnose level and give the evidence for embryonic origin theory of tumorigenesis.Methods Clinical data 2 cases with primary sphenoid sinus craniopharyngioma was analyzed retrospectively,and relevant literature was reviewed.Results Of the 2 cases,the tumors were found occasionally with the symptoms of headache or orbital pain.The tyumor arose from sphenoid sinus,formed a cyst,presenting no homogeneous enhancement after contrast administration in MRI.Intraoperative detection showed the cyst contained yellow viscous liquid in both cases,and with cholesterol crystal in one.The symptoms relieved in both cases,no tumor recurred by 6 months follow-up postoperatively.Conclusion Primary sphenoid sinus craniopharyngiomas has been rarely reported in literature.It may originated in the residual cells of the cranial pharyngeal canal during the migration of Rathke’s pouch in embryonic period.This tumor must be differentiated from chronic sphenoid sinusitis and mucocele cyst.Pathological examination is the only way to confirm the diagnose of craniopharyngiomas.Complete surgical resection is the preferred method for the treatment of this tumor.更多还原