【摘要】 目的探讨输血应用酶联免疫吸附试验(ELISA)检测梅毒螺旋体抗体的临床价值。方法选择2007年1月～2011年1月我院住院接受输血治疗的患者5 790例作为观察对象,应用ELISA试剂盒、TPPA试剂盒进行ELISA和TPPA血清梅毒螺旋体抗体检测。结果 5 790例入选观察对象中,应用ELISA法检测梅毒螺旋体抗体(TP-Ab)阳性50例,阳性率为0.864%;而应用TPPA法检测的梅毒螺旋体抗体阳性49例,阳性率为0.846%(49/5 790)。两种检测方法差异无统计学意义(χ2=0.643,P>0.05)。≥70岁组的应用ELISA法检测的梅毒螺旋体抗体阳性率明显低于<70岁组,差异有统计学意义(P<0.05)。结论输血应用酶联免疫吸附试验(ELISA)检测梅毒螺旋体抗体具有较好的临床价值,与TPPA比较差异不大,值得推广和应用。更多还原

【Abstract】 Objective To investigate the blood enzyme-linked immunosorbent assay(ELISA) antibody detection of Treponema pallidum clinical value.Methods Comparative analysis of two tests used to detect Treponema pallidum antibody positive rate and the different age groups measured by ELISA false-positive rates.Results All of 5 790 cases observed object selected,the application of ELISA to detect Treponema pallidum antibody(TP-Ab) positive,50 cases of the positive rate was 0.864%.The application of TPPA detection of Treponema pallidum antibodies in 49 cases,the positive rate was 0.846%(49/5 790).Miss two detection methods differ significantly(χ2=0.643,P > 0.05).≥70-year-old group,ELISA was used to detect Treponema pallidum antibody positive rate was significantly lower than the <70-year-old group,the difference was statistically significant(P < 0.05).Conclusion Transfusion enzyme-linked immunosorbent assay detection of Treponema pallidum antibody with better clinical value,with little difference between the TPPA,worthy of promotion and application.更多还原