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抗抑郁药对老年冠心病合并抑郁症患者介入手术后的疗效分析

Efficacy of Antidepressant Drugs in Treatment of Coronary Heart Disease with Depression to the Old after PCI

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【作者】 庞可可张珍白云飞王显

【Author】 PANG Ke-ke1,ZHANG Zhen1,BAI Yu-fei2,WANG Xian2(1 The Baotou Sixth People’s Hospital,Baotou 014060,China;2 Beijing Dongzhimen Hospital,Beijing 100086,China)

【机构】 包头第六医院北京东直门医院

【摘要】 目的探讨抗抑郁药对老年冠心病合并抑郁症患者介入手术后抑郁障碍的疗效。方法 80例老年冠心病合并抑郁症患者行经皮冠状动脉成形支架置入术(PCI),后随机分为观察组(米氮平组)和对照组(劳拉西泮组),治疗8周,以汉密顿抑郁量表(HAMD)评定疗效。结果米氮平组和劳拉西泮组减分率分别为63.80%和16.16%,组间差异有显著性。结论介入治疗不能改善冠心病合并抑郁症患者的抑郁症状,抗抑郁药效果确定。

【Abstract】 Objective To explore the efficacy of antidepressant drugs in treatment of coronary heart disease with depression to the old after PCI.Method 80 old coronary heart disease with depression after PCI were randomly divided into study group(mirtazapine group) and contrast group(lorazepam group).The study period was 8 weeks.The Hamilton depression scale was to evaluate the efficacy.Results The reduction rates of the mirtazapine group and contrast group were 63.80% and 16.16% respectively.There was significant difference between the two groups.Conclusion PCI has little efficacy in the treatment of coronary heart disease with depression to the old,the efficacy of antidepressant drugs was definite.

  • 【文献出处】 中国医药指南 ,Guide of China Medicine , 编辑部邮箱 ,2012年07期
  • 【分类号】R749.4
  • 【被引频次】10
  • 【下载频次】88
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