【摘要】 目的观察口服补铁与静脉补铁两种方式对维持性血液透析患者肾性贫血的疗效。方法选取维持性血液透析患者42例,随机分为两组,每组21例,对照组采用重组人促红细胞生成素+口服补充铁剂(力蜚能),治疗组(Ⅱ组)采用重组人促红细胞生成素+静脉补充铁剂(蔗糖铁)。两组均行常规血液透析,2次/周,使用重组人促红细胞生成素治疗,试验时间均为12周。结果与治疗前相比,治疗后两组患者的血红蛋白、红细胞比积、铁蛋白、转铁蛋白饱和度水平均有升高(P<0.05);治疗后各指标治疗组与对照组比较,均有统计学意义(P<0.05)。结论补铁能有效改善维持性血液透析患者的贫血状态,静脉补铁优于口服补铁。更多还原

【Abstract】 Objective To observe the efficacy of oral iron and intravenous iron for treating renal anemic in maintenance hemodialysis.Methods Forty-two patients with maintenance hemodialysis were randomly divided into two groups.The control groupⅠ(n = 21) was treated with recombinant human erythropoietin(rHuEPO) plus oral iron supplement Niferex and the treatment group Ⅱ(n = 21) was treated with rHuEPO plus intravenous iron supplement iron sucrose.Both groups were treated with routine hemodialysis,twice a week for 12 weeks.Results Compared with pretreatment,the levels of Hb,hematocrit(Hct),ferritin and transferrin saturation(TSAT) after treatment in both groups were increased,but compared with the control group,the various indexes in the treatment group showed statistical significance.Conclusion Iron supplement can effectively improve the anemic status in the patients with maintenance hemodialysis.Intravenous iron sucrose supplement is a better treatment than oral iron supplement.更多还原