【摘要】 目的观察血液在不同保存时间内血红蛋白(Hb)、红细胞(RBC)和红细胞压积(HCT)含量的变化。方法取2008年5月～2009年2月264份库存红细胞悬液的血标本,分别于6个时间段(4℃贮存0、7、14、21、28、35 d)测定血红蛋白浓度、红细胞计数和红细胞压积比值。结果血液在保存7、14、21 d,其血红蛋白、红细胞和红细胞压积比值变化并不明显;而血液在保存了28、35 d后的血红蛋白、红细胞和红细胞压积比值与前三组结果比较明显的下降。Hb、RBC、HCT三项检测指标经t检验,差异有统计学意义(P<0.05)。结论血液在体外保存过程中,红细胞的数量、血红蛋白浓度和红细胞压积比值随着血液保存的时间延长而减少和降低,尤其是贮存后期的血液。对于急性失血患者、慢性贫血患者和造血功能障碍患者的输血,应给予保存期较短的血液输注,以提高输血的治疗效果。更多还原

【Abstract】 Objective To observe the changes in the concentration of hemoglobin,the count of erythrocytes and hematocrit of banked blood conversed in different durations.Methods 264 specimens of banked erythrocytic suspension collected from May 2008 to February 2009 were taken and the concentration of hemoglobin,the count of erythrocytes and hematocrit of the specimens were measured after grouping and conserving in six different durations(0 day,7 days,14 days,21 days,28 days and 35 days) under the same temperature(4 celsius degree).Results The changes in specimens which were conserved in 7th day,14th day and 21th day durations were indistinct.Comparing with the former groups,the mentioned indexes in the latter 2 groups evidently showed a decrease or a decline after 28 and 35 days’ conservation.Those indexes were certified by t-test,showing that the consequences were statically significant(P < 0.05).Conclusion In the process of conserving blood in vitro,the concentration of hemoglobin,the count of erythrocytes and hematocrit of banked blood decreases or declines,especially those collected in the earlier time,as the time of conservation extends.In order to improve the therapeutic effect of blood transfusion,patients suffering from acute hemorrhage,chronic anemia or hematopoietic disorder should be treated with recently banked blood.更多还原