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支气管哮喘的中医临床信息评价:中医症状问卷的研制

Evaluation of TCM clinical information in asthma: development of a TCM symptom questionnaire of Asthma

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【作者】 林色奇查青林薛汉荣吕诚肖祖克刘惟优尚云飞陈建建温敏勇吕爱平

【Author】 LIN Seqi1,2 ZHA Qinglin2 XUE Hanrong3 LU Cheng4 XIAO Zuke5 LIU Weiyou6 SHANG Yunfei7 CHEN Jianjian8 WEN Minyong9 LU Aiping4 1.Hu’nan University of Chinese Medicine,Hu’nan Provice,Changsha 410208,China;2.Jiangxi University of TCM,Jiangxi Province,Nanchang 330004,China;3.Institute of Basic Research in Clinical Medicine,China Academy of Chinese Medical Sciences,Beijing 100700,China;4.Affiliated Hospital of Jiangxi University of TCM,Jiangxi Province,Nanchang 330006,China;5.People’s Hospital of Jiangxi Province,Jiangxi Province,Nanchang 330004,China;6.The First Affiliated Hospital of Gannan Medical University,Jiangxi Province,Gannan 341000,China;7.The Third Hospital of Nantong,Affiliated Hospital of Nantong University,Jiangxi Province,Nantong 226006,China;8.Hospitals of Integrated Tcm-Wm of Nanchang,Jiangxi Province,Nanchang 330003,China;The First Affiliated Hospital of Guangzhou University of TCM,Guangdong Province,Guangzhou 510405,China

【机构】 湖南中医药大学研究生院江西中医学院计算机学院江西中医学院附属医院呼吸科中国中医科学院临床基础医学研究所江西省人民医院呼吸科赣南医学院第一附属医院呼吸科南通大学南通第三附属医院呼吸科南昌市中西医结合医院呼吸科广州中医药大学第一附属医院呼吸科

【摘要】 目的研制轻中度支气管哮喘中医症状问卷(traditional Chinese medicine symptoms questionnaire of asthma,TCMSQOA),以补充现代医学支气管哮喘问卷内容,为中医药治疗支气管哮喘临床评价提供一个工具。方法在文献研究和专家咨询的基础上确定支气管哮喘中医症状条目,按照纳入和排除标准从6个临床中心采集支气管哮喘患者中医症状信息,然后分析问卷的信度、效度,以及TCMSQOA与Juniper哮喘生命质量问卷(asthma quality of LifeQuestionnaire,AQLQ)的相关性。结果 TCMSQOA包含28项中医症状条目,概括为5个维度,分别表示哮喘程度(疾病特征)、痰饮、寒、外感、热5个方面。TCMSQOA问卷的内部一致性评价结果 Cronbach’sα系数为:综合分0.90,疾病特征0.88,痰饮0.87,寒0.75,外感0.64,热0.45。TCMSQOA的疾病特征与AQLQ活动受限、哮喘症状和总分相关性较好,相关系数均大于0.7,但两者其他领域之间的相关系数均较小。结论 TCMSQOA能反映轻中度支气管哮喘患者中医症状特征,具有较好的信度和效度,并可补充哮喘疗效评价时痰饮、寒、热及外感方面的信息。

【Abstract】 Objective To develop a traditional Chinese medicine symptoms questionnaire of asthma(TCMSQOA),to complement the content of modern medicine questionnaire of asthma,and to offer a tool to the clinical evaluation of the treatment over asthma.Methods Based on literature research and expert consultant to decide the TCM symptoms’ item of asthma,and according to specified eligibility and elimination criteria to collect the TCM symptoms of asthma from 6 clinical units,and then analyze the reliability and validity of this questionnaire and the dependability between TCMSQOA and asthma quality of life questionnaire(AQLQ).Results TCMSQOA included 28 items of TCM symptom,and summarized to 5 dimensions which denoted disease attributes,phlegm retention,cold,exogenous disease and heat.The Cronbach’sαcoefficient of TCMSQOA in internal conformance assessment were as follow: total score was 0.90,disease attributes was 0.88,phlegm retention was 0.87,cold was 0.75,exogenous disease was 0.64 and heat was 0.45.The relation between the disease attributes of TCMSQOA and limitation of activity,symptoms of asthma and total score of AQLQ has better dependability,which all correlation coefficient were greater than 0.7,but other dimensions has lower correlation coefficient.Conclusion TCMSQOA can reflect the TCM symptoms’ feature of slight and middle degree asthma and has good reliability and validity,which can complement the information of phlegm retention,cold,heat and exogenous disease in evaluating asthma effect.

【基金】 “十一五”国家科技支撑计划资助项目(2006BAI08B02-02);国家自然科学基金资助项目(30825047);江西省卫生厅中医药科研计划资助项目(2008A055)
  • 【文献出处】 中国医药导报 ,China Medical Herald , 编辑部邮箱 ,2012年13期
  • 【分类号】R256.12
  • 【被引频次】18
  • 【下载频次】247
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