【摘要】 目的比较氯氮平与利培酮对精神分裂症患者心理理论的疗效。方法入组的130例被试者中精神分裂症患者家属32例(亲属组)、正常者32例(正常对照组)、精神分裂症患者66例,再将66例精神分裂症患者随机分为两组:服用氯氮平组(34例)和服用利培酮组(32例)。四组患者分别予以失言识别测试,并进行对照研究。结果四组被试者在对照问题上差异无统计学意义(P>0.05);四组失言1、失言2、失言3以及失言4比较差异有统计学意义(P<0.05)。结论精神分裂症存在前额叶认知功能障碍,两种药物对精神分裂症患者心理理论影响无明显差别。更多还原

【Abstract】 Objective To compare the efficacy of clozapine and risperidone on the psychological theory of schizophrenia patients.Methods 130 cases were included in the study,including 32 cases of family member of schizophrenia(kin group),32 normal cases(normal control group),66 cases of patients with schizophrenia;then the 66 cases of schizophrenia were randomly divided into two group:clozapine group(n=34)and risperidone group(n= 32).The four groups of patients took the faux pas recognition test,and were comparatively studied.Results The differences of the control issue among the four groups were not statistically significant(P>0.05);faux pas test differences of the four groups were statistically significant(P<0.05).Conclusion Schizophrenia has prefrontal cognitive dysfunction,no significant difference between the two drugs in influence on the psychological theory of patients with schizophrenia.更多还原