【摘要】 目的对比研究乳腺癌磁共振成像特点与Ki-67表达的关系。方法回顾性分析140例行MR检查并经手术病理证实为乳腺癌患者,80例Ki-67表达阳性,60例阴性。结果乳腺癌Ki-67阳性组比阴性组肿瘤大(P<0.05),更倾向于显示肿块型病变(P<0.05),且更容易出现腋下淋巴结转移(P<0.05)。阳性组的ADC均值比阴性组稍高,但没有统计学意义(P=0.65)。结论乳腺癌Ki-67表达阳性者肿块更大,更易出现淋巴结转移,这可能与细胞增殖活跃相关,也提示患者预后不良。更多还原

【Abstract】 Objective To compare the MR imaging features between Ki-67 positive and negative breast cancers. Methods MRI of 140 patients with histologically confirmed Ki-67 positive(80) and Ki-67 negative(60) invasive ductal carcinomas was retrospectively analyzed.Results Ki-67 positive breast cancer was larger and more likely to show mass lesions(P<0.05) compared to Ki-67 negative cancer that more commonly exhibited non-mass contrast enhancement. Axillary lymph node metastasis was more frequent in Ki-67 positive than Ki-67 negative cancer(P<0.05).The mean ADC value of Ki-67 positive cancer was not significantly higher than the Ki-67 negative cancer(P=0.65).Conclusion Ki-67 positive breast cancer presents as larger mass with lymph node metastasis,which may be related to active cell proliferation and suggests poor prognosis.更多还原